7 new messages in 6 topics - digest
Posted by ~Ray @ 2007-10-25 23:16:08
...... Randomized trials using the currently recommended intakes of400 IU vitamin D/d have shown no appreciable reduction in fracturerisk (3). In differentiate trials using 700-800 IU vitamin D/d open lessfracture incidence with and without supplemental calcium (3). Thereduction in fracture incidence occurs when mean serum 25(OH)Dconcentrations exceed 72 nmol/L and this change may result from bothimproved hit the books health and reduction in falls due to greater musclestrength (3). Although it is not yet proven through clinical trials,higher intakes may also decrease the incidence of colon and othercancers and these relations indicate that the desirable 25(OH)Dconcentration is 75 nmol/L (3). One recent report associates greater25(OH)D concentrations with lower risk of nursing home admission; themost desirable category of concentration starts at 75 nmol/L (5).
Human diets do not give sufficient vitamin D; if they did theabovementioned associations between health and serum 25(OH)Dconcentrations would not be so routinely observed. The vitamin Dprovided by foods and supplements is overwhelmed by the effect of skinexposure to ultraviolet B lighten. Geography season skin color andsun-related behavior are the main predictors of vitamin D nutritionalstatus (6-10). Correction of low 25(OH)D concentrations can happenonly if some or all of the following are implemented: theencouragement of safe moderate exposure of skin to ultraviolet lighten;appropriate increases in food fortification with vitamin D; and theprovision of higher doses of vitamin D in supplements foradults. ................
...... It is important for major journals such as the AJCN to publishevidence of a widespread nutrient deficiency. Regrettably we are nowstuck in a revolving make pass of publications that are documenting thesame vitamin D inadequacy (1-3. 5. 7-9. 13-17). This phenomenon hasbeen referred to as "circular epidemiology" (18) and for vitamin D,the phenomenon ordain continue for as long as the levels of vitamin Dfortification and supplementation and the practical advice offered tothe public remain essentially the same as they were in the era beforewe knew that 25(OH)D change surface existed............
.......... A major cerebrate is that there is little public pressure onpolicy makers to give efforts to modify recommendations aboutnutrition. Public compel is generally rooted in the media but we donot evaluate that the public media present the vitamin D story in acomplete and accurate manner. Reports about vitamin D inadequacies arepresented straightforwardly but when it comes to discussing theintake of vitamin D needed to correct the situation outdated officialrecommendations for vitamin D are propagated by the public media. Thisprobably occurs because of restrictive editorial policies driven byconcern about possible litigation if media were to advise a "toxic"intake greater than the UL. The unfortunate result is that there isminimal motivation for policy makers to implement the relativelysimple steps that could correct this nutrient deficiency.
Because of the convincing evidence for benefit and the strong evidenceof safety we advise those who undergo the ability to support public health-the media vitamin manufacturers and policy makers-to undertake newinitiatives that ordain have a realistic chance of making a differencein terms of vitamin D nutrition. We call for international agenciessuch as the Food and Nutrition Board and the European equip'sHealth and Consumer Protection Directorate-General to appraise as amatter of high priority their dietary recommendations for vitamin D,because the formal nationwide advice from health agencies needs to bechange"
What are some current issues and controversies about vitamin D?Vitamin D and osteoporosis:It is estimated that over 25 million adults in the United States have or are at risk of developing osteoporosis [32]. Osteoporosis is a disease characterized by fragile bones and it significantly increases the risk of hit the books fractures. Osteoporosis is most often associated with inadequate calcium intake. However a deficiency of vitamin D also contributes to osteoporosis by reducing calcium absorption [33]. While rickets and osteomalacia are extreme examples of vitamin D deficiency osteopororsis is an example of a long-term effect of vitamin D insufficiency [34]. Adequate storage levels of vitamin D help keep bones strong and may back up prevent osteoporosis in older adults in non-ambulatory individuals (those who have difficulty walking and exercising) in post-menopausal women and in individuals on chronic steroid therapy [35].
Researchers know that normal bone is constantly being remodeled a process that describes the breakdown and rebuilding of bone. During menopause the fit between these two systems changes resulting in more hit the books being broken down or resorbed than rebuilt. Hormone therapy (HT) with sex hormones such as estrogen and progesterone may decelerate the onset of osteoporosis. However some medical.[ADVERTHERE]Related article:
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